What The Liposomal Encapsulation Means To Clinical Therapy

By Kristen Baird


The use of liposome in clinical medicine first came to trial in the 1960s, and research and clinical trials that have since followed made sure that this amazing technological evolution can now be applied for both clinical therapy and in other aspect of life. However, the liposomal encapsulation technology (LET) is still in its early stages of development, with little information known to the wider public.

Many scientists, researchers and industrialist alike agree that this technology is likely to revolutionize the oral pharmacological therapy and may soon be in realm of use by any common man. Currently, it provides a safer and a unique way of treating the racehorse without having to use the syringes and needles.

In this technology, phospholipid membrane (liposome) is used to encase a prescribed amount of pharmaceutical compounds with the aim of preventing their degradation as they pass through the gastrointestinal tract. This option offers an excellent transfer mechanism that is not available with other drug administration methods. The method is now used in other fields other than in clinical therapies. These include supplement manufacturers, topical moisturizers and the beauty product manufacturers among others.

Phospholipid liposome can withstand the effect of anyone radicals, especially the chemicals, the body dampness, the basic liquids, and the salts inside the digestive tract. The substance enclosed is therefore secured till it gets to the targeted tissue where the cell walls of the tissue cells open allowing the phospholipids and its content inside. The result is a superb method of drug therapy that has minimum impact to functionality of normal body system.

The technology is so effective since it stems from the ability of liposomes to penetrate the cell walls and most other infective microorganisms. This gives it a winning advantage against most of pathogenic infections. In recent research findings, it was established that only 5 grams of Vitamin C that is enclosed in liposome is as effective as up to 50 grams of the same that is administered directly without the liposome casing.

Clearly, the advantages of LET over the other forms of drug delivery are many. It allows nutrients to transport power packed natural compounds to the targeted tissues and organs without discomposing the same. This makes a lot of medical and economic sense. Normally, the drugs would be affected by a number of environmental factors as they pass to the tissues. These include oxygen, moisture, differing pH, and enzymes among others. This in addition to factors that affect absorption of nutrients into the body, such as fillers, sugars, binders, and sugar can cause a problem due to incomplete absorption.

The use of phospholipids also comes with numerous benefits to the body. It cuts down on serum lipids, decreases platelet aggregation, bad cholesterol, triglyceride, and increases good cholesterol, and the fluidity of red blood cells gets amplified. In addition to these, it helps boost immunity, improves quality of memory, protects the liver and improves the ability of the body to endure exercise.

Even though the LET promises to be the most effective method of drug delivery, the old age methods such as capsules, tablets, powder forms and needles must still remain in use. These methods do not disrupt the blood flow in the system which is essential for physical fitness. Ideally, a comprehensive method that considers all the available methods would be better for any clinical therapy.




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